Platform on Molecular Optogenetics

OptoBase is an annotated database, which aims to cover all existing non-opsin-based optogenetic switches and publications. It is meant for both expert optogeneticists, to easily keep track of the field, as well as for all researchers who find optogenetics inviting as a powerful tool to address their biological questions of interest.

Cite as: K. Kolar et al.: OptoBase: A Web Platform for Molecular Optogenetics. ACS Synth. Biol. 2018, DOI: 10.1021/acssynbio.8b00120

News & Updates (see all entries)
Nov. 08, 2024 | Research Highlights in October

This month we dive into the world of optogenetically induced condensates and their application possibilities.

Paper of the Month October: Light-induced targeting enables proteomics on endogenous condensates.

Featured Paper: Optogenetic control of condensates: principles and applications.


Job Offer of the Month:

Scientist in Molecular Optogenetics at Prolific Machines

If you have job openings in molecular optogenetics, we will be happy to post them here. Please contact us at hello@optobase.org.

Oct. 08, 2024 | Welcome to the New OptoBase!

Dear OptoBase Users,

We are excited to announce that OptoBase has undergone a design refresh!
You’ll still find all the information, publications, and your favorite switches - including some brand new switches and tools - right where you expect them.
We hope you enjoy the new look and wish you continued success in your research.

Best regards,
The OptoBase Team

Optogenetic Switches

(see the extended overview of the switches)

Click on a switch for additional information.

UV Violet Blue Cyan Green Yellow Red Far Red
300 nm 400 nm 500 nm 600 nm 700 nm

UV receptors

UVR8/COP1 UVR8/UVR8

Fluorescent proteins

PYP

Fluorescent proteins

Dronpa145K/N Dronpa145N pdDronpa1

Cobalamin-binding domains

MxCBD TtCBD

Phytochromes

BICYCL-Green