euPAC

Photoreceptor euPACα, euPACβ
Binding partner /
Cofactor FAD or FMN
Source organism Euglena gracilis
Mode of action cAMP production
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time seconds
Add a new 3D structure

Related original publications

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  1. Structural insight into photoactivation of an adenylate cyclase from a photosynthetic cyanobacterium. Proc Natl Acad Sci USA, 2016
  2. PACα--an optogenetic tool for in vivo manipulation of cellular cAMP levels, neurotransmitter release, and behavior in Caenorhabditis elegans. J Neurochem, 2011
  3. Light modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa. J Biol Chem, 2010
  4. Functional transplant of photoactivated adenylyl cyclase (PAC) into Aplysia sensory neurons. Neurosci Res, 2007
  5. Fast manipulation of cellular cAMP level by light in vivo. Nat Methods, 2006