iLight

Photoreceptor IsPadC–PCM
Binding partner /
Cofactor Biliverdin
Source organism Idiomarina sp. A28L
Mode of action homodimerization
Excitation wavelength 660 nm
Reversion wavelength 760 nm
Excitation time seconds
Reversion time minutes
Crystal structure of the activated heterodimer of IsPadC, including IsPadC-PCM. (PDB ID: 6ET7)

Related original publications

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  1. Advanced deep-tissue imaging and manipulation enabled by biliverdin reductase knockout. bioRxiv, 2024
  2. Red-Light-Induced Genetic System for Control of Extracellular Electron Transfer. ACS Synth Biol, 2024
  3. Single-component near-infrared optogenetic systems for gene transcription regulation. Nat Commun, 2021