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About
Optogenetic Switches
LOV domains
FKF1/GI
FKF1/GI
Photoreceptor
FKF1
Binding partner
GI
Cofactor
FMN
Source organism
Arabidopsis thaliana
Mode of action
heterodimerization
Excitation wavelength
450 nm
Reversion wavelength
dark
Excitation time
minutes
Reversion time
hours
Add a new 3D structure
Related original publications
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A glucose-blue light AND gate-controlled chemi-optogenetic cell-implanted therapy for treating type-1 diabetes in mice.
Front Bioeng Biotechnol
,
2023
Temporal induction of Lhx8 by optogenetic control system for efficient bone regeneration.
Stem Cell Res Ther
,
2021
Photoactivatable Cre recombinase 3.0 for in vivo mouse applications.
Nat Commun
,
2020
Engineered BRET-Based Biologic Light Sources Enable Spatiotemporal Control over Diverse Optogenetic Systems.
ACS Synth Biol
,
2019
Optogenetic control of mesenchymal cell fate towards precise bone regeneration.
Theranostics
,
2019
Optogenetic Control of Endoplasmic Reticulum-Mitochondria Tethering.
ACS Synth Biol
,
2017
Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1.
Nucleic Acids Res
,
2017
Light-inducible gene regulation with engineered zinc finger proteins.
Methods Mol Biol
,
2014
Light-inducible spatiotemporal control of gene activation by customizable zinc finger transcription factors.
J Am Chem Soc
,
2012
Ca2+ signaling amplification by oligomerization of L-type Cav1.2 channels.
Proc Natl Acad Sci USA
,
2012
Induction of protein-protein interactions in live cells using light.
Nat Biotechnol
,
2009