EL222

Related original publications

1. Balancing doses of EL222 and light improves optogenetic induction of protein production in Komagataella phaffii. bioRxiv, 2025
2. Optogenetic control of Corynebacterium glutamicum gene expression. Nucleic Acids Res, 2024
3. Genetically-stable engineered optogenetic gene switches modulate spatial cell morphogenesis in two- and three-dimensional tissue cultures. Nat Commun, 2024
4. Light-Induced Nanobody-Mediated Targeted Protein Degradation for Metabolic Flux Control. ACS Synth Biol, 2024
5. Optogenetic control of phosphate-responsive genes using single component fusion proteins in Saccharomyces cerevisiae. bioRxiv, 2024
6. Multisite Assembly of Gateway Induced Clones (MAGIC): a flexible cloning toolbox with diverse applications in vertebrate model systems. bioRxiv, 2024
7. Dynamic Multiplexed Control and Modeling of Optogenetic Systems Using the High-Throughput Optogenetic Platform, Lustro. ACS Synth Biol, 2024
8. Multicolor optogenetics for regulating flux ratio of three glycolytic pathways using EL222 and CcaSR in Escherichia coli. Biotechnol Bioeng, 2023
9. Light induced expression of gRNA allows for optogenetic gene editing of T lymphocytes in vivo. bioRxiv, 2023
10. Diya – a universal light illumination platform for multiwell plate cultures. iScience, 2023
11. Multidimensional characterization of inducible promoters and a highly light-sensitive LOV-transcription factor. Nat Commun, 2023
12. A Bioluminescent Activity Dependent (BLADe) Platform for Converting Neuronal Activity to Photoreceptor Activation. bioRxiv, 2023
13. Optogenetic closed-loop feedback control of the unfolded protein response optimizes protein production. Metab Eng, 2023
14. Light inducible protein degradation in E. coli with LOVtag. bioRxiv, 2023
15. Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales. Front Bioeng Biotechnol, 2023
16. Near-Infrared Nano-Optogenetic Activation of Cancer Immunotherapy via Engineered Bacteria. Adv Mater, 2022
17. A Single-Component Blue Light-Induced System Based on EL222 in Yarrowia lipolytica. Int J Mol Sci, 2022
18. Hydrogel microcapsules containing engineered bacteria for sustained production and release of protein drugs. Biomaterials, 2022
19. Synthetic cells with self-activating optogenetic proteins communicate with natural cells. Nat Commun, 2022
20. Synthetic gene networks recapitulate dynamic signal decoding and differential gene expression. Cell Syst, 2022
21. Using single-cell models to predict the functionality of synthetic circuits at the population scale. Proc Natl Acad Sci U S A, 2022
22. Systematic In Vivo Characterization of Fluorescent Protein Maturation in Budding Yeast. ACS Synth Biol, 2022
23. Development of Optogenetic Dual-Switch System for Rewiring Metabolic Flux for Polyhydroxybutyrate Production. Molecules, 2022
24. Design and Characterization of an Optogenetic System in Pichia pastoris. ACS Synth Biol, 2022
25. A light tunable differentiation system for the creation and control of consortia in yeast. Nat Commun, 2021
26. Rapid prototyping and design of cybergenetic single-cell controllers. Nat Commun, 2021
27. Light-Induced GFP Expression in Zebrafish Embryos using the Optogenetic TAEL/C120 System. J Vis Exp, 2021
28. The Neurospora crassa Inducible Q System Enables Simultaneous Optogenetic Amplification and Inversion in Saccharomyces cerevisiae for Bidirectional Control of Gene Expression. ACS Synth Biol, 2021
29. Cellulosic biofuel production using emulsified simultaneous saccharification and fermentation (eSSF) with conventional and thermotolerant yeasts. Biotechnol Biofuels, 2021
30. Optogenetic Amplification Circuits for Light-Induced Metabolic Control. ACS Synth Biol, 2021
31. Blue Light‐Operated CRISPR/Cas13b‐Mediated mRNA Knockdown (Lockdown). Adv Biol, 2021
32. TAEL 2.0: An Improved Optogenetic Expression System for Zebrafish. Zebrafish, 2021
33. Dynamical Modeling of Optogenetic Circuits in Yeast for Metabolic Engineering Applications. ACS Synth Biol, 2021
34. Optogenetics in Sinorhizobium meliloti Enables Spatial Control of Exopolysaccharide Production and Biofilm Structure. ACS Synth Biol, 2021
35. An Optogenetic Platform to Dynamically Control the Stiffness of Collagen Hydrogels. ACS Biomater Sci Eng, 2020
36. Engineering an Optogenetic CRISPRi Platform for Improved Chemical Production. ACS Synth Biol, 2020
37. An Irf6-Esrp1/2 regulatory axis controls midface morphogenesis in vertebrates. Development, 2020
38. Design and Characterization of Rapid Optogenetic Circuits for Dynamic Control in Yeast Metabolic Engineering. ACS Synth Biol, 2020
39. Optogenetic Downregulation of Protein Levels to Control Programmed Cell Death in Mammalian Cells with a Dual Blue-Light Switch. Methods Mol Biol, 2020
40. Optogenetic control of gene expression in plants in the presence of ambient white light. Nat Methods, 2020
41. Light-powered Escherichia coli cell division for chemical production. Nat Commun, 2020
42. Blue Light-Directed Cell Migration, Aggregation, and Patterning. J Mol Biol, 2020
43. Optical induction of autophagy via Transcription factor EB (TFEB) reduces pathological tau in neurons. PLoS ONE, 2020
44. Cell-in-the-loop pattern formation with optogenetically emulated cell-to-cell signaling. Nat Commun, 2020
45. An Open-Source Plate Reader. Biochemistry, 2018
46. Programming the Dynamic Control of Bacterial Gene Expression with a Chimeric Ligand- and Light-Based Promoter System. ACS Synth Biol, 2018
47. Dual-controlled optogenetic system for the rapid down-regulation of protein levels in mammalian cells. Sci Rep, 2018
48. Pulsatile inputs achieve tunable attenuation of gene expression variability and graded multi-gene regulation. Nat Commun, 2018
49. An Optogenetic Platform for Real-Time, Single-Cell Interrogation of Stochastic Transcriptional Regulation. Mol Cell, 2018
50. Cell-free optogenetic gene expression system. ACS Synth Biol, 2018
51. Optogenetic regulation of engineered cellular metabolism for microbial chemical production. Nature, 2018
52. A calcium- and light-gated switch to induce gene expression in activated neurons. Nat Biotechnol, 2017
53. TAEL: a zebrafish-optimized optogenetic gene expression system with fine spatial and temporal control. Development, 2016
54. Blue light-mediated transcriptional activation and repression of gene expression in bacteria. Nucleic Acids Res, 2016
55. An optogenetic gene expression system with rapid activation and deactivation kinetics. Nat Chem Biol, 2014
56. Blue light-induced dimerization of a bacterial LOV-HTH DNA-binding protein. Biochemistry, 2013
57. Blue light-mediated gene expression as a promising strategy to reduce antibiotic resistance in Escherichia coli. Biotechnol J, 2024
58. Construction and Characterization of Light-Responsive Transcriptional Systems. Methods Mol Biol, 2024