pdDronpa1

Photoreceptor pdDronpa1
Binding partner /
Cofactor none
Source organism Pectiniidae
Mode of action homodimerization, dissociation
Excitation wavelength 500 nm
Reversion wavelength 400 nm
Excitation time seconds
Reversion time seconds
Crystal structure of the pdDronpaV (i.e. pdDronpa1 lacking the mutations M40I and V60A) homodimer. Note: No pdDronpa1 structure available at the moment. (PDB ID: 6D39)

Related original publications

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  1. Phased ERK responsiveness and developmental robustness regulate teleost skin morphogenesis. Proc Natl Acad Sci U S A, 2025
  2. Photoswitchable binders enable temporal dissection of endogenous protein function. bioRxiv, 2023
  3. Optical regulation of endogenous RhoA reveals selection of cellular responses by signal amplitude. Cell Rep, 2022
  4. Engineering Photoresponsive Ligand Tethers for Mechanical Regulation of Stem Cells. Adv Mater, 2021
  5. Capicua is a fast-acting transcriptional brake. Curr Biol, 2021
  6. Light-inducible generation of membrane curvature in live cells with engineered BAR domain proteins. ACS Synth Biol, 2020
  7. Optimizing photoswitchable MEK. Proc Natl Acad Sci USA, 2019
  8. A single-chain photoswitchable CRISPR-Cas9 architecture for light-inducible gene editing and transcription. ACS Chem Biol, 2017
  9. Optical control of cell signaling by single-chain photoswitchable kinases. Science, 2017