Mesoscale regulation of MTOCs by the E3 ligase TRIM37. bioRxiv, 2024
Stress pathway outputs are encoded by pH-dependent clustering of kinase components. Nat Commun, 2024
Spatiotemporal Control of Inflammatory Lytic Cell Death Through Optogenetic Induction of RIPK3 Oligomerization. J Mol Biol, 2024
Protein supersaturation powers innate immune signaling. bioRxiv, 2024
Development of an optogenetics tool, Opto-RANK, for control of osteoclast differentiation using blue light. Sci Rep, 2024
Impact of the clinically approved BTK inhibitors on the conformation of full-length BTK and analysis of the development of BTK resistance mutations in chronic lymphocytic leukemia. bioRxiv, 2023
Optogenetic STING clustering system through nanobody-fused photoreceptor for innate immune regulation. Sens Actuators B Chem, 2023
Visual quantification of prostaglandin E2 discharge from a single cell. Cell Struct Funct, 2023
Optogenetic engineering of STING signaling allows remote immunomodulation to enhance cancer immunotherapy. Nat Commun, 2023
Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape. Cell Syst, 2023
Advanced human iPSC-based preclinical model for Parkinson's disease with optogenetic alpha-synuclein aggregation. Cell Stem Cell, 2023
Calcium transients trigger switch-like discharge of prostaglandin E2 (PGE2) in an ERK-dependent manner. bioRxiv, 2023
A nucleation barrier spring-loads the CBM signalosome for binary activation. Elife, 2022
Biophysical and biochemical properties of Deup1 self-assemblies: a potential driver for deuterosome formation during multiciliogenesis. Biol Open, 2021
Non-invasive optical control of endogenous Ca2+ channels in awake mice. Nat Commun, 2020
Flotillins promote T cell receptor sorting through a fast Rab5-Rab11 endocytic recycling axis. Nat Commun, 2019
A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. Nat Commun, 2018
Optogenetic protein clustering through fluorescent protein tagging and extension of CRY2. Nat Commun, 2017
Gene Delivery and Analysis of Optogenetic Induction of Lytic Cell Death. Curr Protoc, 2024