CRY2/CIB1

Related original publications

1. Src kinase slows collective rotation of confined epithelial cell monolayers. Soft Matter, 2024
2. Spatiotemporal control of subcellular O-GlcNAc signaling using Opto-OGT. Nat Chem Biol, 2024
3. Precise Control of Intracellular Trafficking and Receptor-Mediated Endocytosis in Living Cells and Behaving Animals. Adv Sci (Weinh), 2024
4. Optogenetic Control of the Mitochondrial Protein Import in Mammalian Cells. Cells, 2024
5. Rho/Rok-dependent regulation of actomyosin contractility at tricellular junctions controls epithelial permeability in Drosophila. bioRxiv, 2024
6. Precision in situ cryo-correlative light and electron microscopy of optogenetically-positioned organelles. J Cell Sci, 2024
7. Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping. Sci Rep, 2024
8. Atomistic mechanisms of the regulation of small-conductance Ca2+-activated K+ channel (SK2) by PIP2. Proc Natl Acad Sci U S A, 2024
9. PIP5K-Ras bistability initiates plasma membrane symmetry breaking to regulate cell polarity and migration. bioRxiv, 2024
10. Selective optogenetic inhibition of Gαq or Gαi signaling by minimal RGS domains disrupts circuit functionality and circuit formation. Proc Natl Acad Sci U S A, 2024
11. Notch1 Phase Separation Coupled Percolation facilitates target gene expression and enhancer looping. bioRxiv, 2024
12. Optogenetic Strategies for Optimizing the Performance of Phospholipids Biosensors. Adv Sci (Weinh), 2024
13. Self-powered triboelectric-responsive microneedles with controllable release of optogenetically engineered extracellular vesicles for intervertebral disc degeneration repair. Nat Commun, 2024
14. Exploring plant-derived phytochrome chaperone proteins for light-switchable transcriptional regulation in mammals. Nat Commun, 2024
15. TORC1 reactivation by pheromone signaling revealed by phosphoproteomics of fission yeast sexual reproduction. bioRxiv, 2024
16. AGS3-based optogenetic GDI induces GPCR-independent Gβγ signaling and macrophage migration. bioRxiv, 2024
17. Spatiotemporal Control of Inflammatory Lytic Cell Death Through Optogenetic Induction of RIPK3 Oligomerization. J Mol Biol, 2024
18. Shaping an evanescent focus of light for high spatial resolution optogenetic activations in live cells. Opt Express, 2024
19. Spatiotemporal control of subcellular O-GlcNAc signaling using Opto-OGT. bioRxiv, 2024
20. Dynamic Multiplexed Control and Modeling of Optogenetic Systems Using the High-Throughput Optogenetic Platform, Lustro. ACS Synth Biol, 2024
21. Myosin II actively regulates Drosophila proprioceptors. bioRxiv, 2024
22. Optogenetic control of Nodal signaling patterns. bioRxiv, 2024
23. Engineering Material Properties of Transcription Factor Condensates to Control Gene Expression in Mammalian Cells and Mice. Small, 2024
24. Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum. Dev Cell, 2024
25. The Dystrophin-Dystroglycan complex ensures cytokinesis efficiency in Drosophila epithelia. bioRxiv, 2024
26. Phosphatidic acid is an endogenous negative regulator of PIEZO2 channels and mechanical sensitivity. bioRxiv, 2024
27. Epithelial folding through local degradation of an elastic basement membrane plate. bioRxiv, 2024
28. Temporal dynamics of BMP/Nodal ratio drive tissue-specific gastrulation morphogenesis. bioRxiv, 2024
29. Enhancing high-throughput optogenetics: Integration of LITOS with Lustro enables simultaneous light stimulation and shaking. MicroPubl Biol, 2024
30. Using split protein reassembly strategy to optically control PLD enzymatic activity. bioRxiv, 2024
31. Ultralow Background Membrane Editors for Spatiotemporal Control of Phosphatidic Acid Metabolism and Signaling ACS Cent Sci, 2024
32. Optogenetic generation of leader cells reveals a force-velocity relation for collective cell migration. bioRxiv, 2024
33. Development of an optogenetics tool, Opto-RANK, for control of osteoclast differentiation using blue light. Sci Rep, 2024
34. A mechanical wave travels along a genetic guide to drive the formation of an epithelial furrow during Drosophila gastrulation. Dev Cell, 2024
35. A platform to induce and mature biomolecular condensates using chemicals and light. Nat Chem Biol, 2024
36. Engineered poly(A)-surrogates for translational regulation and therapeutic biocomputation in mammalian cells. Cell Res, 2024
37. Bidirectional Allosteric Coupling between PIP2 Binding and the Pore of the Oncochannel TRPV6. Int J Mol Sci, 2024
38. Optogenetic induction of caspase-8 mediated apoptosis by employing Arabidopsis cryptochrome 2. Sci Rep, 2023
39. Spatiotemporal Optical Control of Gαq-PLCβ Interactions. ACS Synth Biol, 2023
40. Liebig’s law of the minimum in the TGF-β/SMAD pathway. bioRxiv, 2023
41. A single-component, light-assisted uncaging switch for endoproteolytic release. Nat Chem Biol, 2023
42. A programmable protease-based protein secretion platform for therapeutic applications. Nat Chem Biol, 2023
43. AAV-compatible optogenetic tools for activating endogenous calcium channels in vivo. Mol Brain, 2023
44. Spatiotemporal, optogenetic control of gene expression in organoids. Nat Methods, 2023
45. Photoactivatable base editors for spatiotemporally controlled genome editing in vivo. Biomaterials, 2023
46. Diya – a universal light illumination platform for multiwell plate cultures. iScience, 2023
47. Cell Cycle Control by Optogenetically Regulated Cell Cycle Inhibitor Protein p21. Biology (Basel), 2023
48. Force propagation between epithelial cells depends on active coupling and mechano-structural polarization. Elife, 2023
49. High-Throughput Optogenetics Experiments in Yeast Using the Automated Platform Lustro. J Vis Exp, 2023
50. Optogenetic strategies for optimizing the performance of biosensors of membrane phospholipids in live cells. bioRxiv, 2023
51. Automatic detection of spatio-temporal signalling patterns in cell collectives. J Cell Biol, 2023
52. Tissue Flows Are Tuned by Actomyosin-Dependent Mechanics in Developing Embryos. PRX Life, 2023
53. Lustro: High-Throughput Optogenetic Experiments Enabled by Automation and a Yeast Optogenetic Toolkit. ACS Synth Biol, 2023
54. Optogenetic control of Cdc48 for dynamic metabolic engineering in yeast. Metab Eng, 2023
55. Mechanosensitive dynamics of lysosomes along microtubules regulate leader cell emergence in collective cell migration. bioRxiv, 2023
56. Concept and considerations of a medical device: the active noise cancelling incubator. Front Pediatr, 2023
57. An optogenetic-phosphoproteomic study reveals dynamic Akt1 signaling profiles in endothelial cells. Nat Commun, 2023
58. Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair. J Nanobiotechnology, 2023
59. Activity-based directed evolution of a membrane editor in mammalian cells. Nat Chem, 2023
60. Actuation of single downstream nodes in growth factor network steers immune cell migration. Dev Cell, 2023
61. Rab8, Rab11, and Rab35 coordinate lumen and cilia formation during zebrafish left-right organizer development. PLoS Genet, 2023
62. OptIC Notch reveals mechanism that regulates receptor interactions with CSL. Development, 2023
63. Directed differentiation of human iPSCs into mesenchymal lineages by optogenetic control of TGF-β signaling. Cell Rep, 2023
64. Optogenetic inhibition of Gα signalling alters and regulates circuit functionality and early circuit formation. bioRxiv, 2023
65. Light Activated BioID (LAB): an optically activated proximity labeling system to study protein-protein interactions. bioRxiv, 2023
66. Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos. J Vis Exp, 2023
67. Optogenetic decoding of Akt2-regulated metabolic signaling pathways in skeletal muscle cells using transomics analysis. Sci Signal, 2023
68. Light-driven biological actuators to probe the rheology of 3D microtissues. Nat Commun, 2023
69. Near-infrared-inducible Bcl-2-associated X protein system for apoptosis regulation in vivo. J Chem Eng, 2023
70. Polarized branched Actin modulates cortical mechanics to produce unequal-size daughters during asymmetric division. Nat Cell Biol, 2023
71. Cell size and actin architecture determine force generation in optogenetically activated cells. Biophys J, 2023
72. An optogenetic tool to inhibit RhoA in Drosophila embryos. STAR Protoc, 2023
73. Golgi screen identifies the RhoGEF Solo as a novel regulator of RhoB and endocytic transport. Traffic, 2022
74. Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles. Nat Commun, 2022
75. An Optogenetic-Controlled Cell Reprogramming System for Driving Cell Fate and Light-Responsive Chimeric Mice. Adv Sci (Weinh), 2022
76. Precision super-resolution cryo-correlative light and electron microscopy for rapid in situ structural analyses of optogenetically-positioned organelles. bioRxiv, 2022
77. Regulation of EGF-stimulated activation of the PI-3K/AKT pathway by exocyst-mediated exocytosis. Proc Natl Acad Sci U S A, 2022
78. Patterned mechanical feedback establishes a global myosin gradient. Nat Commun, 2022
79. Mechanistic insights into cancer drug resistance through optogenetic PI3K signaling hyperactivation. Cell Chem Biol, 2022
80. Stable Transgenic Mouse Strain with Enhanced Photoactivatable Cre Recombinase for Spatiotemporal Genome Manipulation. Adv Sci (Weinh), 2022
81. Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration. Nat Cell Biol, 2022
82. Spatiotemporal control of ERK pulse frequency coordinates fate decisions during mammary acinar morphogenesis. Dev Cell, 2022
83. Optogenetic manipulation of cell migration with high spatiotemporal resolution using lattice lightsheet microscopy. Commun Biol, 2022
84. LITOS: a versatile LED illumination tool for optogenetic stimulation. Sci Rep, 2022
85. Light-activated mitochondrial fission through optogenetic control of mitochondria-lysosome contacts. Nat Commun, 2022
86. Optical regulation of endogenous RhoA reveals selection of cellular responses by signal amplitude. Cell Rep, 2022
87. Microtubule disassembly by caspases is an important rate-limiting step of cell extrusion. Nat Commun, 2022
88. Spindle reorientation in response to mechanical stress is an emergent property of the spindle positioning mechanisms. Proc Natl Acad Sci U S A, 2022
89. Precise control of microtubule disassembly in living cells. EMBO J, 2022
90. Transcription activation is enhanced by multivalent interactions independent of phase separation. Mol Cell, 2022
91. Light-dependent modulation of protein localization and function in living bacteria cells. bioRxiv, 2022
92. Light-induced fermenter production of derivatives of the sweet protein monellin is maximized in prestationary Saccharomyces cerevisiae cultures. Biotechnol J, 2022
93. Cell division in tissues enables macrophage infiltration. Science, 2022
94. Upregulated flotillins and sphingosine kinase 2 derail AXL vesicular traffic to promote epithelial-mesenchymal transition. J Cell Sci, 2022
95. An optogenetic tool to recruit individual PKC isozymes to the cell surface and promote specific phosphorylation of membrane proteins. J Biol Chem, 2022
96. Optogenetic Control of PIP2 Interactions Shaping ENaC Activity. Int J Mol Sci, 2022
97. The cell polarity determinant Dlg1 facilitates epithelial invagination by promoting tissue-scale mechanical coordination. Development, 2022
98. Synthetic gene networks recapitulate dynamic signal decoding and differential gene expression. Cell Syst, 2022
99. Optogenetic inhibition of actomyosin reveals mechanical bistability of the mesoderm epithelium during Drosophila mesoderm invagination. Elife, 2022
100. Spatio-temporal, optogenetic control of gene expression in organoids. bioRxiv, 2022
101. Mechanical strain stimulates COPII-dependent trafficking via Rac1. bioRxiv, 2022
102. Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins. Nat Biotechnol, 2022
103. CeLINC, a fluorescence-based protein-protein interaction assay in Caenorhabditis elegans. Genetics, 2021
104. Optogenetic relaxation of actomyosin contractility uncovers mechanistic roles of cortical tension during cytokinesis. Nat Commun, 2021
105. Nano-optogenetic engineering of CAR T cells for precision immunotherapy with enhanced safety. Nat Nanotechnol, 2021
106. Cell patterning by secretion-induced plasma membrane flows. Sci Adv, 2021
107. An active tethering mechanism controls the fate of vesicles. Nat Commun, 2021
108. Revisiting the Role of TGFβ Receptor Internalization for Smad Signaling: It is Not Required in Optogenetic TGFβ Signaling Systems. Adv Biol (Weinh), 2021
109. Mechanical competition alters the cellular interpretation of an endogenous genetic programme. J Cell Biol, 2021
110. Optogenetic Tools for Control of Public Goods in Saccharomyces cerevisiae. mSphere, 2021
111. Mapping the dynamic transfer functions of eukaryotic gene regulation. Cell Syst, 2021
112. Mechanical worrying drives cell migration in crowded environments. bioRxiv, 2021
113. Rab11 endosomes coordinate centrosome number and movement following mitotic exit. bioRxiv, 2021
114. Using optogenetics to link myosin patterns to contractile cell behaviors during convergent extension. Biophys J, 2021
115. Light-inducible deformation of mitochondria in live cells. Cell Chem Biol, 2021
116. Collective ERK/Akt activity waves orchestrate epithelial homeostasis by driving apoptosis-induced survival. Dev Cell, 2021
117. Exosome-based delivery of super-repressor IκBα ameliorates kidney ischemia-reperfusion injury. Kidney Int, 2021
118. Optogenetic Control of the Canonical Wnt Signaling Pathway During Xenopus laevis Embryonic Development. J Mol Biol, 2021
119. Random sub-diffusion and capture of genes by the nuclear pore reduces dynamics and coordinates inter-chromosomal movement. Elife, 2021
120. PIP2 regulation of TRPC5 channel activation and desensitization. J Biol Chem, 2021
121. Optogenetic-based Localization of Talin to the Plasma Membrane Promotes Activation of β3 Integrins. J Biol Chem, 2021
122. A modular tool to query and inducibly disrupt biomolecular condensates. Nat Commun, 2021
123. A single-chain and fast-responding light-inducible Cre recombinase as a novel optogenetic switch. Elife, 2021
124. CRISPR-dcas9 Optogenetic Nanosystem for the Blue Light-Mediated Treatment of Neovascular Lesions. ACS Appl Bio Mater, 2021
125. Transient light-activated gene expression in Chinese hamster ovary cells. BMC Biotechnol, 2021
126. A CRISPR-Cas9-Based Near-Infrared Upconversion-Activated DNA Methylation Editing System. ACS Appl Mater Interfaces, 2021
127. A synthetic BRET-based optogenetic device for pulsatile transgene expression enabling glucose homeostasis in mice. Nat Commun, 2021
128. Control of SRC molecular dynamics encodes distinct cytoskeletal responses by specifying signaling pathway usage. J Cell Sci, 2021
129. Optogenetic Control of Phosphatidylinositol (3,4,5)‐triphosphate Production by Light‐sensitive Cryptochrome Proteins on the Plasma Membrane. Chin J Chem, 2021
130. Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling. J Biol Chem, 2021
131. Living materials with programmable functionalities grown from engineered microbial co-cultures. Nat Mater, 2021
132. A Light-Inducible Split-dCas9 System for Inhibiting the Progression of Bladder Cancer Cells by Activating p53 and E-cadherin. Front Mol Biosci, 2021
133. Liquid-liquid phase separation of light-inducible transcription factors increases transcription activation in mammalian cells and mice. Sci Adv, 2021
134. Efficient photoactivatable Dre recombinase for cell type-specific spatiotemporal control of genome engineering in the mouse. Proc Natl Acad Sci U S A, 2020
135. Increased lateral tension is sufficient for epithelial folding in Drosophila. Development, 2020
136. Regulating enzymatic reactions in Escherichia coli utilizing light-responsive cellular compartments based on liquid-liquid phase separation. bioRxiv, 2020
137. Single-Protein Tracking to Study Protein Interactions During Integrin-Based Migration. Methods Mol Biol, 2020
138. Multichromatic Control of Signaling Pathways in Mammalian Cells. Adv Biosyst, 2020
139. Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in Drosophila. Elife, 2020
140. Control of Cell Migration Using Optogenetics. Methods Mol Biol, 2020
141. Activation of Cdc42 GTPase upon CRY2-Induced Cortical Recruitment Is Antagonized by GAPs in Fission Yeast. Cells, 2020
142. CL6mN: Rationally Designed Optogenetic Photoswitches with Tunable Dissociation Dynamics. ACS Synth Biol, 2020
143. A non-invasive far-red light-induced split-Cre recombinase system for controllable genome engineering in mice. Nat Commun, 2020
144. Photo-SNAP-tag, a Light-Regulated Chemical Labeling System. ACS Chem Biol, 2020
145. Optogenetic Control of Gene Expression Using Cryptochrome 2 and a Light-Activated Degron. Methods Mol Biol, 2020
146. βH-spectrin is required for ratcheting apical pulsatile constrictions during tissue invagination. EMBO Rep, 2020
147. Early But Not Delayed Optogenetic RAF Activation Promotes Astrocytogenesis in Mouse Neural Progenitors. J Mol Biol, 2020
148. Photoactivatable RNA N6 -Methyladenosine Editing with CRISPR-Cas13. Small, 2020
149. Dual Function of PI(4,5)P2 in Insulin-Regulated Exocytic Trafficking of GLUT4 in Adipocytes. J Mol Biol, 2020
150. ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization. Dev Cell, 2020
151. CofActor: A light- and stress-gated optogenetic clustering tool to study disease-associated cytoskeletal dynamics in living cells. J Biol Chem, 2020
152. Optical Activation of TrkB Signaling. J Mol Biol, 2020
153. CLIC4 is a cytokinetic cleavage furrow protein that regulates cortical cytoskeleton stability during cell division. J Cell Sci, 2020
154. Photoactivatable Cre recombinase 3.0 for in vivo mouse applications. Nat Commun, 2020
155. Optogenetic stimulation of phosphoinositides reveals a critical role of primary cilia in eye pressure regulation. Sci Adv, 2020
156. Phosphatidylinositol 4,5-bisphosphate directly interacts with the β and γ subunits of the sodium channel ENaC. J Biol Chem, 2020
157. Exosome-based delivery of super-repressor IκBα relieves sepsis-associated organ damage and mortality. Sci Adv, 2020
158. A Generalizable Optogenetic Strategy to Regulate Receptor Tyrosine Kinases during Vertebrate Embryonic Development. J Mol Biol, 2020
159. Cytokinetic bridge triggers de novo lumen formation in vivo. Nat Commun, 2020
160. Tissue-Scale Mechanical Coupling Reduces Morphogenetic Noise to Ensure Precision during Epithelial Folding. Dev Cell, 2020
161. Spatiotemporal control of phosphatidic acid signaling with optogenetic, engineered phospholipase Ds. J Cell Biol, 2020
162. Mps1-mediated release of Mad1 from nuclear pores ensures the fidelity of chromosome segregation. J Cell Biol, 2020
163. Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling. Nat Commun, 2020
164. Engineering light-controllable CAR T cells for cancer immunotherapy. Sci Adv, 2020
165. Pulsatile MAPK Signaling Modulates p53 Activity to Control Cell Fate Decisions at the G2 Checkpoint for DNA Damage. Cell Rep, 2020
166. Optogenetic control of mRNA localization and translation in live cells. Nat Cell Biol, 2020
167. Cell and tissue manipulation with ultrashort infrared laser pulses in light-sheet microscopy. Sci Rep, 2020
168. Optogenetics reveals Cdc42 local activation by scaffold-mediated positive feedback and Ras GTPase. PLoS Biol, 2020
169. Shape-morphing living composites. Sci Adv, 2020
170. Tunable light and drug induced depletion of target proteins. Nat Commun, 2020
171. Stick-slip dynamics of cell adhesion triggers spontaneous symmetry breaking and directional migration of mesenchymal cells on one-dimensional lines. Sci Adv, 2020
172. Engineered BRET-Based Biologic Light Sources Enable Spatiotemporal Control over Diverse Optogenetic Systems. ACS Synth Biol, 2019
173. Primary Cilia Signaling Promotes Axonal Tract Development and Is Disrupted in Joubert Syndrome-Related Disorders Models. Dev Cell, 2019
174. Directed evolution improves the catalytic efficiency of TEV protease. Nat Methods, 2019
175. Blue light-triggered optogenetic system for treating uveal melanoma. Oncogene, 2019
176. A yeast optogenetic toolkit (yOTK) for gene expression control in Saccharomyces cerevisiae. Biotechnol Bioeng, 2019
177. Optogenetic inhibition of Delta reveals digital Notch signaling output during tissue differentiation. EMBO Rep, 2019
178. Imaging of Morphological and Biochemical Hallmarks of Apoptosis with Optimized Optogenetic Actuators. PLoS ONE, 2019
179. Flotillins promote T cell receptor sorting through a fast Rab5-Rab11 endocytic recycling axis. Nat Commun, 2019
180. Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs. Nat Biotechnol, 2019
181. FRET-assisted photoactivation of flavoproteins for in vivo two-photon optogenetics. Nat Methods, 2019
182. Secretory Vesicle Clustering in Fungal Filamentous Cells Does Not Require Directional Growth. Cell Rep, 2019
183. Light-Induced Transcription Activation for Time-Lapse Microscopy Experiments in Living Cells. Methods Mol Biol, 2019
184. Transient Activations of Rac1 at the Lamellipodium Tip Trigger Membrane Protrusion. Curr Biol, 2019
185. Optogenetic gene editing in regional skin. Cell Res, 2019
186. Achieving tight control of a photoactivatable Cre recombinase gene switch: new design strategies and functional characterization in mammalian cells and rodent. Nucleic Acids Res, 2019
187. Cross-linker-mediated regulation of actin network organization controls tissue morphogenesis. J Cell Biol, 2019
188. LADL: light-activated dynamic looping for endogenous gene expression control. Nat Methods, 2019
189. OpEn-Tag-A Customizable Optogenetic Toolbox To Dissect Subcellular Signaling. ACS Synth Biol, 2019
190. Accurate manipulation of optogenetic proteins with wavelength tunable femtosecond laser system. J Appl Phys, 2019
191. Reversible Optogenetic Control of Growth Factor Signaling During Cell Differentiation and Vertebrate Embryonic Development. OSA Technical Digest, 2019
192. Self-Organized Nuclear Positioning Synchronizes the Cell Cycle in Drosophila Embryos. Cell, 2019
193. Cortical mitochondria regulate insulin secretion by local Ca2+ buffering. J Cell Sci, 2019
194. Advances in optogenetic regulation of gene expression in mammalian cells using cryptochrome 2 (CRY2). Methods, 2019
195. Optogenetic perturbation of the biochemical pathways that control cell behavior. Meth Enzymol, 2019
196. Design, construction, and validation of optogenetic proteins. Lancet Diabetes Endocrinol, 2019
197. Physical Plasma Membrane Perturbation Using Subcellular Optogenetics Drives Integrin-Activated Cell Migration. ACS Synth Biol, 2019
198. Light-Induced Protein Clustering for Optogenetic Interference and Protein Interaction Analysis in Drosophila S2 Cells. Biomolecules, 2019
199. Near-infrared light remotely up-regulate autophagy with spatiotemporal precision via upconversion optogenetic nanosystem. Biomaterials, 2019
200. A Photoactivatable Botulinum Neurotoxin for Inducible Control of Neurotransmission. Neuron, 2019
201. Noninvasive optical activation of Flp recombinase for genetic manipulation in deep mouse brain regions. Nat Commun, 2019
202. Blue Light Switchable Cell–Cell Interactions Provide Reversible and Spatiotemporal Control Towards Bottom-Up Tissue Engineering. Adv Biosyst, 2019
203. Enhanced intrinsic CYP3A4 activity in human hepatic C3A cells with optically controlled CRISPR/dCas9 activator complex. Integr Biol (Camb), 2018
204. Development of a Wireless-Controlled LED Array for the Tunable Optogenetic Control of Cellular Activities. Engineering, 2018
205. Optogenetic dissection of Rac1 and Cdc42 gradient shaping. Nat Commun, 2018
206. Downregulation of basal myosin-II is required for cell shape changes and tissue invagination. EMBO J, 2018
207. Membrane dynamics induced by a PIP3 optogenetic tool. Anal Sci, 2018
208. Real-Time Genetic Compensation Defines the Dynamic Demands of Feedback Control. Cell, 2018
209. RalB directly triggers invasion downstream Ras by mobilizing the Wave complex. Elife, 2018
210. Light Control of the Tet Gene Expression System in Mammalian Cells. Cell Rep, 2018
211. Optogenetic control of epithelial-mesenchymal transition in cancer cells. Sci Rep, 2018
212. A Single-Component Optogenetic System Allows Stringent Switch of Gene Expression in Yeast Cells. ACS Synth Biol, 2018
213. Spatiotemporal control of zebrafish (Danio rerio) gene expression using a light-activated CRISPR activation system. Gene, 2018
214. Optical activation of TrkA signaling. ACS Synth Biol, 2018
215. Synthetic far-red light-mediated CRISPR-dCas9 device for inducing functional neuronal differentiation. Proc Natl Acad Sci USA, 2018
216. Guided morphogenesis through optogenetic activation of Rho signalling during early Drosophila embryogenesis. Nat Commun, 2018
217. Independent Control over Multiple Cell Types in Space and Time Using Orthogonal Blue and Red Light Switchable Cell Interactions. Adv Sci, 2018
218. A platform of BRET-FRET hybrid biosensors for optogenetics, chemical screening, and in vivo imaging. Sci Rep, 2018
219. Regulation of cell cycle progression by cell-cell and cell-matrix forces. Nat Cell Biol, 2018
220. Optogenetic inhibition of Gαq protein signaling reduces calcium oscillation stochasticity. ACS Synth Biol, 2018
221. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. Nat Commun, 2018
222. Analysis of the CaMKIIα and β splice-variant distribution among brain regions reveals isoform-specific differences in holoenzyme formation. Sci Rep, 2018
223. A biochemical network controlling basal myosin oscillation. Nat Commun, 2018
224. Optogenetic Control of Cell Migration. Methods Mol Biol, 2018
225. Light-activated protein interaction with high spatial subcellular confinement. Proc Natl Acad Sci USA, 2018
226. Generation of Optogenetically Modified Adenovirus Vector for Spatiotemporally Controllable Gene Therapy. ACS Chem Biol, 2018
227. Unique Roles of β-Arrestin in GPCR Trafficking Revealed by Photoinducible Dimerizers. Sci Rep, 2018
228. Spatiotemporal Control of TGF-β Signaling with Light. ACS Synth Biol, 2017
229. Gradients of Rac1 Nanoclusters Support Spatial Patterns of Rac1 Signaling. Cell Rep, 2017
230. Real-time observation of light-controlled transcription in living cells. J Cell Sci, 2017
231. Optogenetic regulation of artificial microRNA improves H2 production in green alga Chlamydomonas reinhardtii. Biotechnol Biofuels, 2017
232. Propagating Wave of ERK Activation Orients Collective Cell Migration. Dev Cell, 2017
233. Near-Infrared Light Triggered Upconversion Optogenetic Nanosystem for Cancer Therapy. ACS Nano, 2017
234. Design and Profiling of a Subcellular Targeted Optogenetic cAMP-Dependent Protein Kinase. Cell Chem Biol, 2017
235. Optimized light-inducible transcription in mammalian cells using Flavin Kelch-repeat F-box1/GIGANTEA and CRY2/CIB1. Nucleic Acids Res, 2017
236. A single-chain photoswitchable CRISPR-Cas9 architecture for light-inducible gene editing and transcription. ACS Chem Biol, 2017
237. Understanding CRY2 interactions for optical control of intracellular signaling. Nat Commun, 2017
238. CRISPR-Cas9-based photoactivatable transcription systems to induce neuronal differentiation. Nat Methods, 2017
239. Two independent but synchronized Gβγ subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration. J Biol Chem, 2017
240. Photo-Activatable Akt Probe - A New Tool to Study the Akt-Dependent Physiopathology of Cancer Cells. Oncol Res, 2017
241. An Engineered Optogenetic Switch for Spatiotemporal Control of Gene Expression, Cell Differentiation, and Tissue Morphogenesis. ACS Synth Biol, 2017
242. Vesicle Docking Is a Key Target of Local PI(4,5)P2 Metabolism in the Secretory Pathway of INS-1 Cells. Cell Rep, 2017
243. A calcium- and light-gated switch to induce gene expression in activated neurons. Nat Biotechnol, 2017
244. Optogenetic activation of Plexin-B1 reveals contact repulsion between osteoclasts and osteoblasts. Nat Commun, 2017
245. Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development. J Vis Exp, 2017
246. Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2. Nucleic Acids Res, 2017
247. Cell-matrix adhesion and cell-cell adhesion differentially control basal myosin oscillation and Drosophila egg chamber elongation. Nat Commun, 2017
248. Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain. Nat Methods, 2017
249. Light-Regulated Protein Kinases Based on the CRY2-CIB1 System. Methods Mol Biol, 2017
250. Optogenetic control of cellular forces and mechanotransduction. Nat Commun, 2017
251. Epigenetic Editing of Ascl1 Gene in Neural Stem Cells by Optogenetics. Sci Rep, 2017
252. Optogenetic Control of Synaptic Composition and Function. Neuron, 2017
253. Transcription activator-like effector-mediated regulation of gene expression based on the inducible packaging and delivery via designed extracellular vesicles. Biochem Biophys Res Commun, 2017
254. A Photoactivatable Innate Immune Receptor for Optogenetic Inflammation. ACS Chem Biol, 2016
255. Plasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for Cytokinesis. Cell Rep, 2016
256. Optogenetic inhibition of apical constriction during Drosophila embryonic development. Methods Cell Biol, 2016
257. An open-hardware platform for optogenetics and photobiology. Sci Rep, 2016
258. A photoactivatable Cre-loxP recombination system for optogenetic genome engineering. Nat Chem Biol, 2016
259. Reversible optogenetic control of kinase activity during differentiation and embryonic development. Development, 2016
260. Optogenetic regulation of site-specific subtelomeric DNA methylation. Oncotarget, 2016
261. Exosome engineering for efficient intracellular delivery of soluble proteins using optically reversible protein-protein interaction module. Nat Commun, 2016
262. Using HEK293T Expression System to Study Photoactive Plant Cryptochromes. Front Plant Sci, 2016
263. The Timing of Raf/ERK and AKT Activation in Protecting PC12 Cells against Oxidative Stress. PLoS ONE, 2016
264. Optogenetic activation reveals distinct roles of PIP3 and Akt in adipocyte insulin action. J Cell Sci, 2016
265. Optimized second-generation CRY2-CIB dimerizers and photoactivatable Cre recombinase. Nat Chem Biol, 2016
266. Optogenetic oligomerization of Rab GTPases regulates intracellular membrane trafficking. Nat Chem Biol, 2016
267. Optogenetically controlled RAF to characterize BRAF and CRAF protein kinase inhibitors. Sci Rep, 2016
268. Frequency and amplitude control of cortical oscillations by phosphoinositide waves. Nat Chem Biol, 2016
269. An Optogenetic Method to Modulate Cell Contractility during Tissue Morphogenesis. Dev Cell, 2015
270. Predictive Spatiotemporal Manipulation of Signaling Perturbations Using Optogenetics. Biophys J, 2015
271. Correlating in Vitro and in Vivo Activities of Light-Inducible Dimers: A Cellular Optogenetics Guide. ACS Synth Biol, 2015
272. An optogenetic system for interrogating the temporal dynamics of Akt. Sci Rep, 2015
273. Optogenetic Control of Gene Expression in Drosophila. PLoS ONE, 2015
274. Photo-activatable Cre recombinase regulates gene expression in vivo. Sci Rep, 2015
275. Optogenetic apoptosis: light-triggered cell death. Angew Chem Int Ed Engl, 2015
276. Photoactivatable CRISPR-Cas9 for optogenetic genome editing. Nat Biotechnol, 2015
277. The Dual Characteristics of Light-Induced Cryptochrome 2, Homo-oligomerization and Heterodimerization, for Optogenetic Manipulation in Mammalian Cells. ACS Synth Biol, 2015
278. Optogenetic control of molecular motors and organelle distributions in cells. Chem Biol, 2015
279. A light-inducible CRISPR-Cas9 system for control of endogenous gene activation. Nat Chem Biol, 2015
280. CRISPR-Cas9-based photoactivatable transcription system. Chem Biol, 2015
281. Optogenetic control of organelle transport and positioning. Nature, 2015
282. Single-molecule tracking of small GTPase Rac1 uncovers spatial regulation of membrane translocation and mechanism for polarized signaling. Proc Natl Acad Sci USA, 2015
283. Benchmarking of optical dimerizer systems. ACS Synth Biol, 2014
284. Engineered UV-A light-responsive gene expression system for measuring sun cream efficacy in mammalian cell culture. J Biotechnol, 2014
285. Optogenetic engineering: light-directed cell motility. Angew Chem Int Ed Engl, 2014
286. Subcellular optogenetic inhibition of G proteins generates signaling gradients and cell migration. Mol Biol Cell, 2014
287. Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling. Nat Commun, 2014
288. Reversible protein inactivation by optogenetic trapping in cells. Nat Methods, 2014
289. Bidirectional regulation of mRNA translation in mammalian cells by using PUF domains. Angew Chem Int Ed Engl, 2014
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