PixD/PixE

Photoreceptor PixD
Binding partner PixE
Cofactor FAD or FMN
Source organism Synechocystis sp. PCC 6803
Mode of action heterooligomerization, dissociation
Excitation wavelength 450 nm
Reversion wavelength dark
Excitation time seconds
Reversion time minutes
Crystal structure of the PixD photoreceptor decamer, without PixE. (PDB ID: 2HFN)

Related original publications

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  1. Regulatable assembly of synthetic microtubule architectures using engineered MAP-IDR condensates. bioRxiv, 2023
  2. Light-based control of metabolic flux through assembly of synthetic organelles. Nat Chem Biol, 2019
  3. Protein Phase Separation Provides Long-Term Memory of Transient Spatial Stimuli. Cell Syst, 2018
  4. Blue light-mediated manipulation of transcription factor activity in vivo. ACS Chem Biol, 2013