Responses to drug therapy in ulcerative colitis. Evaluation by rectal biopsy and histopathological changes.
blue
cyan
green
near-infrared
red
UV
BlrP1b
Cobalamin-binding domains
Cryptochromes
Fluorescent proteins
LOV domains
PAC (BlaC)TtCBD
Phytochromes
UV receptors
Review
Abstract:
To evaluate responses to medical therapy in ulcerative colitis, rectal biopsies of patients with active untreated disease, individuals with positive and negative sigmoidoscopic findings treated with salicylazosulfapyridine, prednisone and 6-mercaptopurine, alone and in combinations and noncolitis controls were compared histologically. Predominant histological observations were analyzed statistically. There were fewer crypt abscesses but more mucosal edema after all forms of therapy. Quantitative histopathological analysis failed to demonstrate that the response to one drug was significantly different from another.
