Engineering Proteins at Interfaces: From Complementary Characterization to Material Surfaces with Designed Functions.
Abstract:
Once materials come in contact with a biological fluid containing proteins, proteins are generally - so desired or not - attracted by a material's surface and adsorb onto it. The aim of this review is to give an overview of the most commonly used characterization methods employed to obtain a better understanding of the adsorption processes on either planar or curved surfaces. We continue to illustrate the benefit of combining different methods to different surface geometries of the material. The thus obtained insights ideally pave the way for engineering functional materials interacting in a predetermined manner with proteins.